Nose Microrobots Show Success in Treating Stubborn Sinusitis

Key Takeaways

1. Tiny robots, about the size of a dust particle, are being developed to treat stubborn bacterial infections in deep body cavities like the sinuses.
2. These photocatalytic microrobots are made from copper-doped bismuth oxoiodide and can be precisely directed to infection areas using an external magnetic field.
3. The therapy involves using optical fibers to transmit visible light to the targeted area, enhancing the effectiveness of the treatment.
4. The robots can be easily removed from the body after treatment, showing potential for non-invasive procedures.
5. While pre-clinical trials have shown promise, it may take several years before this innovative method is available for clinical use.


Swarms of tiny robots, each about the size of a dust particle, are set to change the way we tackle stubborn bacterial infections, especially those hidden deep within the body’s intricate cavities, like the sinuses. A group of researchers from various universities in China and Hong Kong has developed this innovative technique, which aims to break down the challenges that standard treatments often encounter.

Advanced Technology Behind the Robots

The foundation of this cutting-edge therapeutic approach is its photocatalytic microrobots. These tiny devices are not just ordinary machines; they are carefully crafted from copper (Cu) single atom–doped bismuth oxoiodide (BiOI). Once they are injected into the sinus cavity through a slim catheter inserted via the nostril, these CBMR swarms are precisely directed to the infection area using an external magnetic field. Doctors can monitor their journey in real-time with the help of X-ray imaging.

Unique Therapy Method

The true brilliance lies in the therapy that utilizes optical fiber assistance. A separate optical fiber, which is also placed inside the body, transmits visible light straight to the targeted area. This light accomplishes two functions:

After they finish their job, these minuscule doctors can be easily removed from the body, for example, by being blown out through the nose into a tissue. The effectiveness of this approach has already been proven in thorough vivo tests, using a model of rabbit sinusitis. The results were quite encouraging, showing their ability to eliminate infections without causing noticeable tissue damage, indicating their promise for future clinical applications.

Future of Clinical Use

Even though pre-clinical trials have shown success, it may take several years before this method is available for clinical use — until then, traditional methods will have to do. One product that can assist with sinusitis is a sinus pressure relief mask (curr. $35.98 on Amazon), which is designed to help relieve sinusitis, migraines, and headaches.

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