Successful Study of Non-Invasive Blood Glucose Monitor in China

Key Takeaways

1. A new non-invasive blood glucose monitor has been developed by researchers at Ruijin Hospital in Shanghai, which shows promising results for tracking blood glucose levels.

2. The device achieved a mean absolute relative difference (MARD) of 14.6%, which meets the international standard for accuracy in blood glucose monitoring systems.

3. The monitoring device provided non-invasive readings that were 99.4% clinically acceptable based on a study involving 230 participants.

4. Diabetes affects over 10% of the global adult population, with projections indicating a rise to 783 million people by 2045.

5. The non-invasive device allows users to measure blood sugar levels painlessly through depth-selective spectral imaging, eliminating the need for frequent finger pricks.


Information has surfaced about a novel non-invasive blood glucose monitor in the China Daily (Hong Kong). Additionally, a research paper discussing this device has been submitted to Springer Nature for peer evaluation. Researchers from Ruijin Hospital in Shanghai have created a machine that effectively tracks blood glucose levels while maintaining an acceptable mean absolute relative difference (MARD). MARD is critical for managing blood glucose as it requires a certain degree of precision in measurement outcomes.

Device Performance

The research group reported that their non-invasive blood glucose monitoring device achieved a relative difference of 14.6% when comparing measurements taken non-invasively with those taken invasively (using blood samples from veins). According to the international standard for blood glucose monitoring systems (ISO 15197:2013), a system is deemed “sufficiently accurate” if it operates within a 15% difference. Moreover, the unnamed device from the Chinese team allegedly provided non-invasive measurement outcomes that were 99.4% “clinically acceptable.” These encouraging results stemmed from a follow-up study that included 230 participants, comprising 200 individuals with diabetes and 30 without.

Diabetes Impact

In 2021, diabetes types 1 and 2 impacted more than 10% of the global adult population, equating to around 537 million people, with projections suggesting that by 2045, approximately 783 million people could be affected by the disease. The frequent finger pricking for blood sugar tests is an unpleasant chore for those managing diabetes, with some patients needing to test their blood sugar levels up to 10 times daily. The non-invasive blood glucose monitor utilized by the Shanghai team allows patients to simply place their hand in the device, where accurate information is gathered painlessly through depth-selective spectral imaging.

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